Prostate adenocarcinoma: Difference between revisions
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m →Microscopic evaluation: Noted |
Described |
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}} | }} | ||
{{Comprehensiveness}} | |||
==Gross processing== | ==Gross processing== | ||
As '''[[prostatectomy]]''' or biopsy. | As '''[[prostatectomy]]''' or biopsy. | ||
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File:Micrograph of prostate cancer with Gleason pattern 10 (5+5).jpg|Gleason pattern 10 (5+5).jpg | File:Micrograph of prostate cancer with Gleason pattern 10 (5+5).jpg|Gleason pattern 10 (5+5).jpg | ||
</gallery> | </gallery> | ||
Gleason score is as follows:<ref name=JohnHopkins>{{cite web|url=http://pathology.jhu.edu/prostatecancer/newgradingsystem.cfm|title=New Contemporary Prostate Cancer Grading System|website=Johns Hopkins University, Department of Pathology|accessdate=2020-09-21}}</ref> | |||
*Gleason score '''≤3''': Only individual discrete well-formed glands | |||
*Gleason score '''4''': Poorly-formed, fused and/or cribriform glands | |||
*Gleason scores '''5''': Lacks gland formation , or with necrosis | |||
<gallery mode=packed heights=170> | <gallery mode=packed heights=170> | ||
File:Micrograph of prostate cancer with Gleason score 6 (3+3).jpg|Gleason score 6 (3+3) | File:Micrograph of prostate cancer with Gleason score 6 (3+3).jpg|Gleason score 6 (3+3) | ||
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File:Micrograph of prostate cancer with Gleason score 10 (5+5) with solid sheets of cells.jpg|Gleason score 10 (5+5) with solid sheets of cells | File:Micrograph of prostate cancer with Gleason score 10 (5+5) with solid sheets of cells.jpg|Gleason score 10 (5+5) with solid sheets of cells | ||
</gallery> | </gallery> | ||
====Grade group==== | |||
{{Moderate-begin}}In a moderately comprehensive report, also state the overall grade group for the adenocarcinoma:<ref name=JohnHopkins/> | |||
*Grade group '''1''' (Gleason score ≤6) - Only individual discrete well-formed glands | |||
*Grade group '''2''' (Gleason score 3+4=7) - Predominantly well-formed glands with a lesser component of poorly-formed, fused and/or cribriform glands | |||
*Grade group '''3''' (Gleason score 4+3=7) - Predominantly poorly-formed, fused, and/or cribriform glands with a lesser component of well-formed glands | |||
*Grade group '''4''' (Gleason score 8), either of the following | |||
:*Only poorly-formed, fused and/or cribriform glands | |||
:*Predominantly well-formed glands with a lesser component that lacks glands | |||
:*Predominantly lacking glands with a lesser component of well-formed glands | |||
*Grade group '''5''' (Gleason scores 9-10): Any area that lacks gland formation, or with necrosis{{Moderate-end}} | |||
===Staging=== | ===Staging=== | ||
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===Report=== | ===Report=== | ||
*'''Diagnosis''' | *'''Diagnosis''' | ||
*'''Gleason score''' | *'''Gleason score''', and optionally grade group | ||
*'''Extent''' | *'''Extent''' | ||
:*Prostatectomy: '''Stage'''. | :*Prostatectomy: '''Stage'''. | ||
:*Prostate '''biopsies''': '''Number''' of biopsies where tumor is found, and '''percentage''' of involvement in those cases.<ref group=notes>Percentage of involvement can be estimate by first estimated what percentage of the field-of-view diameter the tumorous area occupies, or how many field-of-view diameters it occupies, divided by how many field-of-view diameters the entire biopsy occupies. | :*Prostate '''biopsies''': '''Number''' of biopsies where tumor is found, and '''percentage''' of involvement in those cases.<ref group=notes>Percentage of involvement can be estimate by first estimated what percentage of the field-of-view diameter the tumorous area occupies, or how many field-of-view diameters it occupies, divided by how many field-of-view diameters the entire biopsy occupies. | ||
:*Any '''perineural''' or '''angiolymphatic''' invasion. | :*Any '''perineural''' or '''angiolymphatic''' invasion. | ||
{|class=wikitable | |||
| (Prostate, left apex, needle biopsy:) | |||
prostatic adenocarcinoma, gleason score 3+3 = 6 (grade | |||
group 1), involving 30% of out of one core. | |||
{{Reporting}} | {{Reporting}} | ||
{{Bottom}} | {{Bottom}} | ||