Vulva: Difference between revisions
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==Microscopic examination== | ==Microscopic examination== | ||
[[File:Histopathology of high-grade squamous intraepithelial lesion (HSIL) of vulva.jpg|thumb|Histopathology of high-grade squamous intraepithelial lesion (HSIL) of vulva (left) with full thickness dysplasia, compared to normal epithelium at right.]] | [[File:Histopathology of high-grade squamous intraepithelial lesion (HSIL) of vulva.jpg|thumb|Histopathology of '''high-grade squamous intraepithelial lesion (HSIL)''' of vulva (left in image) with full thickness dysplasia, compared to normal epithelium at right.]] | ||
Mainly look for squamous vulvar intraepithelial lesions: | Mainly look for squamous vulvar intraepithelial lesions: | ||
*'''Low-grade squamous intraepithelial lesion (LSIL)''':<ref name=Choschzick>{{cite web|url=https://www.pathologyoutlines.com/topic/vulvaVIN.html|title=Vulva, vagina & female urethra - Squamous carcinoma and precursor lesions - HPV associated SIL|author=Matthias Choschzick|website=PathologyOutlines}} Topic Completed: 6 January 2021. Minor changes: 11 June 2021</ref> | *'''Low-grade squamous intraepithelial lesion (LSIL)''':<ref name=Choschzick>{{cite web|url=https://www.pathologyoutlines.com/topic/vulvaVIN.html|title=Vulva, vagina & female urethra - Squamous carcinoma and precursor lesions - HPV associated SIL|author=Matthias Choschzick|website=PathologyOutlines}} Topic Completed: 6 January 2021. Minor changes: 11 June 2021</ref> | ||
Revision as of 09:05, 8 September 2021
Author:
Mikael Häggström [note 1]
Gross processing
Generally as per skin.
Microscopic examination
_of_vulva.jpg)
Mainly look for squamous vulvar intraepithelial lesions:
- Low-grade squamous intraepithelial lesion (LSIL):[1]
- Acanthosis, papillomatosis, and/or atypical koilocytosis in upper layers
- Usually mild atypia and mitoses, limited to the lower third of stratum spinosum and basale
- Binucleated epithelial cells
- High-grade squamous intraepithelial lesion (HSIL):[1]
- Enlarged atypical nuclei and mitoses involving middle and upper third of the epithelium.
- Also telling are atypical mitoses and/or extension in hair follicles and skin appendages.
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Matthias Choschzick. Vulva, vagina & female urethra - Squamous carcinoma and precursor lesions - HPV associated SIL. PathologyOutlines. Topic Completed: 6 January 2021. Minor changes: 11 June 2021
Image sources