Prostate adenocarcinoma: Difference between revisions
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File:Micrograph of prostate cancer with Gleason score 10 (5+5) with solid sheets of cells.jpg|Gleason score 10 (5+5) with '''solid sheets''' of cells | File:Micrograph of prostate cancer with Gleason score 10 (5+5) with solid sheets of cells.jpg|Gleason score 10 (5+5) with '''solid sheets''' of cells | ||
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In case of 3 patterns in one specimen:<ref name="MOLAVI p. ">{{cite book | last=MOLAVI | first=DIANA WEEDMAN | title=PRACTICE OF SURGICAL PATHOLOGY : a beginner's guide to the diagnostic process. | publisher=SPRINGER INTERNATIONAL PU | publication-place=[Place of publication not identified] | date=2018 | isbn=3-319-86570-6 | oclc=1085201203 | page=}}</ref> | |||
*On a '''biopsy''': most common pattern + the highest pattern. For example, mostly pattern 3, a bit of 4, and a tiny bit of 5 would be graded 3 + 5 = 8. | |||
*On a '''prostatectomy''': First and second most prevalent patterns, and if there is a minor or third component of higher grade, that is termed a tertiary pattern. The same example as above would be classified as 3 + 4 = 7 with tertiary pattern 5. | |||
{{Comprehensive-begin}}In cases of Gleason pattern 3+4 and 4+3, also state the percentage of Gleason pattern 4 compared to the entire tumor area.<ref name="pmid30363387">{{cite journal| author=Sharma M, Miyamoto H| title=Percent Gleason pattern 4 in stratifying the prognosis of patients with intermediate-risk prostate cancer. | journal=Transl Androl Urol | year= 2018 | volume= 7 | issue= Suppl 4 | pages= S484-S489 | pmid=30363387 | doi=10.21037/tau.2018.03.20 | pmc=6178316 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30363387 }} </ref>{{Comprehensive-end}} | {{Comprehensive-begin}}In cases of Gleason pattern 3+4 and 4+3, also state the percentage of Gleason pattern 4 compared to the entire tumor area.<ref name="pmid30363387">{{cite journal| author=Sharma M, Miyamoto H| title=Percent Gleason pattern 4 in stratifying the prognosis of patients with intermediate-risk prostate cancer. | journal=Transl Androl Urol | year= 2018 | volume= 7 | issue= Suppl 4 | pages= S484-S489 | pmid=30363387 | doi=10.21037/tau.2018.03.20 | pmc=6178316 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30363387 }} </ref>{{Comprehensive-end}} | ||