Cirrhosis: Difference between revisions
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===Gross examination=== | ===Gross examination=== | ||
Cirrhosis is characterized by pale areas. Categorize into either of the following: (1) micronodular or diffuse, (2) macronodular, or (3) mixed:<ref name=ncbi>{{cite web|url= | Cirrhosis is characterized by pale areas. Categorize into either of the following: (1) micronodular or diffuse, (2) macronodular, or (3) mixed:<ref name=ncbi>{{cite web|url=https://www.ncbi.nlm.nih.gov/books/NBK482419/|title=Hepatic Cirrhosis|author=Bashar Sharma; Savio John.|website=StatPearls at the National Center for Biotechnology Information}} Last Update: June 3, 2019.</ref> | ||
[[File:Gross pathology of alcoholic liver cirrhosis.jpg|thumb|Diffuse areas of pallor.]] | [[File:Gross pathology of alcoholic liver cirrhosis.jpg|thumb|Diffuse areas of pallor.]] | ||
*Micronodular or diffuse cirrhosis (uniform nodules less than 3 mm in diameter).<ref group="notes">Micronodular or diffuse cirrhosis can be due to alcohol, hemochromatosis, hepatic venous outflow obstruction, chronic biliary obstruction, jejunoileal bypass, and Indian childhood cirrhosis.</ref> | *Micronodular or diffuse cirrhosis (uniform nodules less than 3 mm in diameter).<ref group="notes">Micronodular or diffuse cirrhosis can be due to alcohol, hemochromatosis, hepatic venous outflow obstruction, chronic biliary obstruction, jejunoileal bypass, and Indian childhood cirrhosis.</ref> | ||
Revision as of 07:02, 11 November 2019
Author:
Mikael Häggström [note 1]
Cirrhosis of the liver:
Gross processing
Template:Gross processing of the liver
Gross examination
Cirrhosis is characterized by pale areas. Categorize into either of the following: (1) micronodular or diffuse, (2) macronodular, or (3) mixed:[1]
- Micronodular or diffuse cirrhosis (uniform nodules less than 3 mm in diameter).[notes 1]
- Macronodular cirrhosis (irregular nodules with a variation greater than 3 mm in diameter): Cirrhosis due to hepatitis B and C, alpha-1 antitrypsin deficiency, and primary biliary cholangitis.
-
Pale macronodules of cirrhosis
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- Mixed cirrhosis (when features of both micronodular and macronodular cirrhosis are present): Usually micronodular cirrhosis progresses into macronodular cirrhosis over time.
Microscopic evaluation
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Components:[1]
- Diagnosing cirrhosis. The diagnosis of cirrhosis by biopsy requires the presence of fibrosis and nodules.
- Assessing the degree of inflammation (grade) and fibrosis (stage) of the disease.
Notes
- ↑ Micronodular or diffuse cirrhosis can be due to alcohol, hemochromatosis, hepatic venous outflow obstruction, chronic biliary obstruction, jejunoileal bypass, and Indian childhood cirrhosis.
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Bashar Sharma; Savio John.. Hepatic Cirrhosis. StatPearls at the National Center for Biotechnology Information. Last Update: June 3, 2019.
Image sources