Cirrhosis: Difference between revisions
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Cirrhosis of the [[liver]]: | Cirrhosis of the [[liver]]: | ||
==Gross processing | ==Gross processing== | ||
In [[autopsy]], make consecutive liver slices, such as in the sagittal or coronal plane. | |||
===Gross examination=== | ===Gross examination=== | ||
Revision as of 03:02, 20 December 2019
Author:
Mikael Häggström [note 1]
Cirrhosis of the liver:
Gross processing
In autopsy, make consecutive liver slices, such as in the sagittal or coronal plane.
Gross examination
Cirrhosis is characterized by pale areas. Categorize into either of the following: (1) micronodular, (2) macronodular, or (3) mixed:[1]
- Micronodular or diffuse cirrhosis (uniform nodules less than 3 mm in diameter).[notes 1]
- Macronodular cirrhosis (irregular nodules with a variation greater than 3 mm in diameter).
-
Pale macronodules of cirrhosis
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- Mixed cirrhosis (when features of both micronodular and macronodular cirrhosis are present): Usually micronodular cirrhosis progresses into macronodular cirrhosis over time.
Microscopic evaluation
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Components:[1]
- Diagnosing cirrhosis. The diagnosis of cirrhosis by biopsy requires the presence of fibrosis and nodules.
- Assessing the degree of inflammation (grade) and fibrosis (stage) of the disease.
Notes
- ↑ Micronodular or diffuse cirrhosis can be due to alcohol, hemochromatosis, hepatic venous outflow obstruction, chronic biliary obstruction, jejunoileal bypass, and Indian childhood cirrhosis.
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Bashar Sharma; Savio John.. Hepatic Cirrhosis. StatPearls at the National Center for Biotechnology Information. Last Update: June 3, 2019.
Image sources