Peripheral blood smear: Difference between revisions
Jump to navigation
Jump to search
Oil immersion |
→Red blood cells: +Table |
||
| Line 19: | Line 19: | ||
| > 26% || Severe anisocytosis | | > 26% || Severe anisocytosis | ||
|} | |} | ||
{|class=wikitable | |||
! Red blood cell abnormality !! Threshold for reporting<ref name="pmid25774322">{{cite journal| author=Horn CL, Mansoor A, Wood B, Nelson H, Higa D, Lee LH | display-authors=etal| title=Performance of the CellaVision(®) DM96 system for detecting red blood cell morphologic abnormalities. | journal=J Pathol Inform | year= 2015 | volume= 6 | issue= | pages= 11 | pmid=25774322 | doi=10.4103/2153-3539.151922 | pmc=4355826 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25774322 }} </ref> | |||
|- | |||
! Acanthocytes | |||
| >5% | |||
|- | |||
! Basophilic stippling | |||
| >2% | |||
|- | |||
! Burr cells | |||
| >10% | |||
|- | |||
! Howell-Jolly bodies | |||
| Any amount | |||
|- | |||
! Ovalocytes | |||
| >10% | |||
|- | |||
! Pappenheimer bodies | |||
| Any amount | |||
|- | |||
! Polychromasia | |||
| >5% | |||
|- | |||
! RBC agglutination | |||
| Any amount | |||
|- | |||
! Rouleaux | |||
| >40% | |||
|- | |||
! Schistocytes | |||
| >2% | |||
|- | |||
! Sickle cells | |||
| Any amount | |||
|- | |||
! Spherocytes | |||
| >2% | |||
|- | |||
! Stomatocytes | |||
| >10% | |||
|- | |||
! Target cells | |||
| >10% | |||
|- | |||
! Tear drop cells | |||
| >2% | |||
|} | |||
When available, automatic quantification of mean corpuscular volume (MCV) and red blood cell (RBC) distribution width (RDW), usually as part of CBC panel, generally decides whether you will call the sample "'''normocytic'''" versus "microcytic"/"macrocytic" and/or "anisocytotic", even if it is not clearly visible in the microscope. If automated values are not available, compare RBC sizes to lymphocyte nuclei, which should normally be the same size. If mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) are normal, but you still see multiple RBCs with central pallor greater than 50% of the diameter, you can report it as ''"Increased central pallor"'', and you may add ''"indicating iron deficiency"'' if it is compatible with the clinical history. | When available, automatic quantification of mean corpuscular volume (MCV) and red blood cell (RBC) distribution width (RDW), usually as part of CBC panel, generally decides whether you will call the sample "'''normocytic'''" versus "microcytic"/"macrocytic" and/or "anisocytotic", even if it is not clearly visible in the microscope. If automated values are not available, compare RBC sizes to lymphocyte nuclei, which should normally be the same size. If mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) are normal, but you still see multiple RBCs with central pallor greater than 50% of the diameter, you can report it as ''"Increased central pallor"'', and you may add ''"indicating iron deficiency"'' if it is compatible with the clinical history. | ||