Vulva: Difference between revisions
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:*Enlarged atypical nuclei and mitoses involving middle and upper third of the epithelium. | :*Enlarged atypical nuclei and mitoses involving middle and upper third of the epithelium. | ||
:*Also telling are atypical mitoses and/or extension in hair follicles and skin appendages. | :*Also telling are atypical mitoses and/or extension in hair follicles and skin appendages. | ||
*'''[[Squamous cell carcinoma of the skin|Squamous cell carcinoma (SCC) of the skin]]'''. | |||
===Staging of vulvar cancer=== | |||
Tumors of the vulva are staged as per the AJCC, 8th Ed:<ref>{{AJCC-8}}</ref>.<ref>{{AJCC-8}}</ref> | |||
{{Bottom}} | {{Bottom}} | ||
Revision as of 16:04, 7 April 2022
Author:
Mikael Häggström [note 1]
Gross processing
Generally as per skin.
Microscopic examination
_of_vulva.jpg){kind=link}
Mainly look for squamous vulvar intraepithelial lesions:
- Low-grade squamous intraepithelial lesion (LSIL):[1]
- Acanthosis, papillomatosis, and/or atypical koilocytosis in upper layers
- Usually mild atypia and mitoses, limited to the lower third of stratum spinosum and basale
- Binucleated epithelial cells
- High-grade squamous intraepithelial lesion (HSIL):[1]
- Enlarged atypical nuclei and mitoses involving middle and upper third of the epithelium.
- Also telling are atypical mitoses and/or extension in hair follicles and skin appendages.
Staging of vulvar cancer
Tumors of the vulva are staged as per the AJCC, 8th Ed:[2].[3]
Notes
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
Main page
References
- ↑ 1.0 1.1 Matthias Choschzick. Vulva, vagina & female urethra - Squamous carcinoma and precursor lesions - HPV associated SIL. PathologyOutlines. Topic Completed: 6 January 2021. Minor changes: 11 June 2021
- ↑ Amin, Mahul (2017). AJCC cancer staging manual
(8 ed.). Switzerland: Springer. ISBN 978-3-319-40617-6. OCLC 961218414.
- For access, see the Secrets chapter of Patholines.
- Copyright note: The AJCC, 8th Ed. is published by a company in Switzerland, and the tables presented therein are Public Domain because they consist of tabular information without literary or artistic innovation, and therefore do not fulfil the inclusion criterion of the Swiss Copyright Act (CopA) which applies to "literary and artistic intellectual creations with individual character" (see Federal Act on Copyright and Related Rights (Copyright Act, CopA) of 9 October 1992 (Status as of 1 January 2022)). - ↑ Amin, Mahul (2017). AJCC cancer staging manual
(8 ed.). Switzerland: Springer. ISBN 978-3-319-40617-6. OCLC 961218414.
- For access, see the Secrets chapter of Patholines.
- Copyright note: The AJCC, 8th Ed. is published by a company in Switzerland, and the tables presented therein are Public Domain because they consist of tabular information without literary or artistic innovation, and therefore do not fulfil the inclusion criterion of the Swiss Copyright Act (CopA) which applies to "literary and artistic intellectual creations with individual character" (see Federal Act on Copyright and Related Rights (Copyright Act, CopA) of 9 October 1992 (Status as of 1 January 2022)).
Image sources