Nasal cavity and paranasal sinuses: Difference between revisions

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File:Histopathology of sinonasal inflammatory polyp with mixed inflammation, annotated.jpg|'''Benign chronic mixed inflammation''' of an inflammatory sinonasal polyp.
File:Histopathology of sinonasal inflammatory polyp with mixed inflammation, annotated.jpg|'''Benign chronic mixed inflammation''' of an inflammatory sinonasal polyp.
File:Histopathology of acute sinusitis.png|'''Acute inflammation''' characterized by neutrophils.
File:Histopathology of extranodal NK-T cell lymphoma, nasal type.png|'''Extranodal NK/T cell lymphoma, nasal type'''.<ref>{{cite journal| author=Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y| title=Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation. | journal=Microorganisms | year= 2021 | volume= 9 | issue= 7 | pages=  | pmid=34202088 | doi=10.3390/microorganisms9071381 | pmc=8304202 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=34202088  }}<br>- "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."</ref> These lymphoma cells are typically monotonous, with folded nuclei, indistinct nucleoli and moderate amount of cytoplasm.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/lymphomanonBnasal.html|title=Extranodal NK / T cell lymphoma, nasal type|author=Mario L. Marques-Piubelli, M.D., Carlos A. Torres-Cabala, M.D., Roberto N. Miranda, M.D.|website=Pathology Outlines}} Last author update: 5 January 2021. Last staff update: 14 October 2021</ref>
File:Histopathology of extranodal NK-T cell lymphoma, nasal type.png|'''Extranodal NK/T cell lymphoma, nasal type'''.<ref>{{cite journal| author=Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y| title=Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation. | journal=Microorganisms | year= 2021 | volume= 9 | issue= 7 | pages=  | pmid=34202088 | doi=10.3390/microorganisms9071381 | pmc=8304202 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=34202088  }}<br>- "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."</ref> These lymphoma cells are typically monotonous, with folded nuclei, indistinct nucleoli and moderate amount of cytoplasm.<ref>{{cite web|url=https://www.pathologyoutlines.com/topic/lymphomanonBnasal.html|title=Extranodal NK / T cell lymphoma, nasal type|author=Mario L. Marques-Piubelli, M.D., Carlos A. Torres-Cabala, M.D., Roberto N. Miranda, M.D.|website=Pathology Outlines}} Last author update: 5 January 2021. Last staff update: 14 October 2021</ref>
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Latest revision as of 15:17, 14 June 2024

Author: Mikael Häggström [note 1]

Comprehensiveness

On this resource, the following formatting is used for comprehensiveness:

  • Minimal depth
  • (Moderate depth)
  • ((Comprehensive))

Nasal or sinonasal polyps

Look for signs of malignancy. Further information: Evaluation of suspected malignancies

File:Histopathology of a nasal polyp.jpg
Benign nasal/sinonasal polyp (not otherwise specified), consisting of hyperplastic edematous connective tissue with some seromucous glands and inflammation (mostly neutrophils and eosinophils), surrounded by respiratory or squamous epithelium.[1] It can be termed inflammatory nasal/sinonasal polyp when inflammation is more pronounced.

Main differential diagnoses:

In case of significant inflammation:

  • Take at least one high magnification look to confirm that it is mixed and that lymphocytes are not atypical (otherwise, consult hematopathology, particularly whether it could be a lymphoma, notably extranodal NK/T cell lymphoma, nasal type.
  • (Classify as acute (with neutrophils) versus chronic (lymphocytes, eosinophils and/or plasma cells). Also look at any bone fragments for osteomyelitis.) Further information: Osteomyelitis

Reporting

Example:

Right and left sinus contents, excisions:
Benign respiratory mucosa with chronic inflammation.
Bone without significant histopathologic changes.

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Michaels, Leslie (2012-12-06) (in en). Ear, Nose and Throat Histopathology . Springer Science & Business Media. p. 168. ISBN 9781447133322. 
  2. Takahara M, Kumai T, Kishibe K, Nagato T, Harabuchi Y (2021). "Extranodal NK/T-Cell Lymphoma, Nasal Type: Genetic, Biologic, and Clinical Aspects with a Central Focus on Epstein-Barr Virus Relation. ". Microorganisms 9 (7). doi:10.3390/microorganisms9071381. PMID 34202088. PMC: 8304202. Archived from the original. . 
    - "This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."
  3. Mario L. Marques-Piubelli, M.D., Carlos A. Torres-Cabala, M.D., Roberto N. Miranda, M.D.. Extranodal NK / T cell lymphoma, nasal type. Pathology Outlines. Last author update: 5 January 2021. Last staff update: 14 October 2021

Image sources