Duodenum

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Author: Mikael Häggström [note 1]

Endoscopic biopsies   edit
Mostly:

Common requests

Microscopic examination

Generally look for:

  • Signs of peptic duodenitis
  • Intra-epithelial lymphocytes
  • Tumors
  • Giardia organisms

Peptic duodenitis

Peptic duodenitis typically showing the following:[1]

Others

Report

Example in a normal case:

(Duodenum, biopsy:) Duodenal mucosa without significant histopathologic changes. (Negative for celiac disease.)

Example in (chronic) peptic duodenitis:

(Small bowel, biopsy:) Small intestinal mucosa with histologic changes consistent with chronic peptic duodenitis. (Negative for celiac disease.)

Notes

  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page

References

  1. Hasan Samra, M.D., Mohamed Mostafa, M.D.. Small intestine & ampulla - Inflammatory disorders - Peptic duodenitis. Pathology Outlines. Topic Completed: 13 April 2020. Minor changes: 13 April 2020
  2. "Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') ". Gastroenterology 102 (1): 330–54. 1992. doi:10.1016/0016-5085(92)91819-p. PMID 1727768. 
  3. Biagi F, Luinetti O, Campanella J, Klersy C, Zambelli C, Villanacci V (2004). "Intraepithelial lymphocytes in the villous tip: do they indicate potential coeliac disease? ". J Clin Pathol 57 (8): 835-9. doi:10.1136/jcp.2003.013607. PMID 15280404. PMC: 1770380. Archived from the original. . 
  4. 4.0 4.1 Juwairiya Arshi, M.B.B.S., Aaron R. Huber, D.O.. Small intestine & ampulla. Malabsorption. Celiac sprue. Pathology Outlines. Retrieved on 2022-04-04.

Image sources

  1. "Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue') ". Gastroenterology 102 (1): 330–54. 1992. doi:10.1016/0016-5085(92)91819-p. PMID 1727768. 
    - Figure 2- available via license: Creative Commons Attribution 2.0 Generic license.