Fibrocystic breast changes
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Sclerosing adenosis, with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.
- Not be lobular at low power
- Have marked cellular atypia
- Have no myoepithelial cells surrounding duccts.
When unsure, perform immunohistochemistry for calponin:
- Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.. Breast - Fibrocystic changes - Sclerosing adenosis. Pathology Outlines. Topic Completed: 1 January 2015. Minor changes: 31 December 2020