Liver tumor

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Author: Mikael Häggström [notes 1]
A tumor of the liver:

Tissue sampling

  • Liver biopsy
  • Autopsy: Further information: Autopsy

Gross examination

Note the following:[1]

  • Whether the tumor is sell demarcated from surrounding tissue
  • Whether there is visible infiltration or invasion into surrounding tissue
  • Any necrosis or bleeding

Microscopic evaluation

A bile duct hamartoma is also very common.[2] This image shows typical features:[3]
- Small to medium sized, irregularly shaped bile ducts lined by bland cuboidal epithelium (may also be flattened).
- Prominent intervening collagenous stroma.
- Bile ducts containing eosinophilic debris (may also contain inspissated bile)

Further information: Evaluation of suspected malignancies


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

Main page


  1. . General oncology. Amboss. Retrieved on 2020-01-29.
  2. Yang, Xiao-Yu; Zhang, Hai-Bo; Wu, Bin; Li, Ai-Jun; Fu, Xiao-Hui (2017). "Surgery is the preferred treatment for bile duct hamartomas ". Molecular and Clinical Oncology 7 (4): 649–653. doi:10.3892/mco.2017.1354. ISSN 2049-9450. 
  3. Upasana Joneja, M.D.. Liver & intrahepatic bile ducts - Developmental anomalies / cysts - Von Meyenburg complex. Pathology Outlines. Topic Completed: 23 November 2020. Minor changes: 23 November 2020
  4. Table 37.2 in: Sternberg, Stephen (2012). Sternberg's diagnostic surgical pathology . Place of publication not identified: LWW. ISBN 978-1-4511-5289-0. OCLC 953861627. 
  5. Figure 7 from Bioulac-Sage, Paulette; Sempoux, Christine; Possenti, Laurent; Frulio, Nora; Laumonier, Hervé; Laurent, Christophe; Chiche, Laurence; Frédéric Blanc, Jean; et al. (2013). "Pathological Diagnosis of Hepatocellular Cellular Adenoma according to the Clinical Context ". International Journal of Hepatology 2013: 1–13. doi:10.1155/2013/253261. ISSN 2090-3448. 
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