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Author: Mikael Häggström [notes 1]

TURP: Gross processing

For fragments obtained from transurethral resection of the prostate (TURP):[1]

  • Weigh and measure tissue aggregate in 3 dimensions.
  • If weight is less than or equal to 12 gm: Submit entirely in biopsy bags (usually approximately 12 cassettes).
  • If weight is more than 12 gm: Submit 12 grams in biopsy bags, and 1 additional cassette per each additional 5 grams.

Prostatectomy: Gross processing

  • For orientation, apply ink or make a cut to one half of the specimen, and possibly a different one to the other side.[2]
Prostate cutting.png

The transverse slices may be cut into quadrants if exceeding laboratory capacity.

See also: General notes on gross processing

Most common targets


Screening method

  • Before microscopy, look at each microscopy slide by eye, to plan the microscopy screening so as to not miss peripheral fragments.
  • Screen at low power, and switch to high power when encountering glandular structures that can not otherwise be cleared. Look in particular for those surrounding nerves.
  • At least if no cancer is seen, also look for inflammation.[notes 2]

Common normal findings

  • Infoldings in prostate glands.
  • Rectum tissue, by transrectal approach such as biopsies.


Example in a normal case:

(Prostate, right base, needle biopsy:)

Benign prostate tissue


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
  2. Inflammation can explain for example a high PSA value in the absence of adenocarcinoma, so its reporting is usually only needed in such cases.

Main page


  1. Nicole Cipriani. Prostate: TURP. Gross Pathology Manual - The University of Chicago Department of Pathology.
  2. Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.