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TURP: Gross processing
For fragments obtained from transurethral resection of the prostate (TURP):
- Weigh and measure tissue aggregate in 3 dimensions.
- If weight is less than or equal to 12 gm: Submit entirely in biopsy bags (usually approximately 12 cassettes).
- If weight is more than 12 gm: Submit 12 grams in biopsy bags, and 1 additional cassette per each additional 5 grams.
Prostatectomy: Gross processing
- For orientation, apply ink or make a cut to one half of the specimen, and possibly a different one to the other side.
The transverse slices may be cut into quadrants if exceeding laboratory capacity.
- See also: General notes on gross processing
Most common targets
- Prostate adenocarcinoma, including cases of high PSA
- Before microscopy, look at each microscopy slide by eye, to plan the microscopy screening so as to not miss peripheral fragments.
- Screen at low power, and switch to high power when encountering glandular structures that can not otherwise be cleared. Look in particular for those surrounding nerves.
- At least if no cancer is seen, also look for inflammation.[notes 2]
Common normal findings
- Infoldings in prostate glands.
- Rectum tissue, by transrectal approach such as biopsies.
Example in a normal case:
|(Prostate, right base, needle biopsy:)|
Benign prostate tissue
- For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
- Inflammation can explain for example a high PSA value in the absence of adenocarcinoma, so its reporting is usually only needed in such cases.