Fibrocystic breast changes
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Mikael Häggström [note 1]
Sclerosing adenosis, with an increase in glandular elements in addition to stromal proliferation that distorts and compresses glands.
Sclerosing adenosis may look similar to invasive ductal carcinoma (IDC), but IDC will:
- Not be lobular at low power
- Have marked cellular atypia
- Have no myoepithelial cells surrounding ducts.
When unsure, perform immunohistochemistry for myoepithelial markers (preferably p63 and calponin in breast lesions):
- ↑ For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.
- ↑ 1.0 1.1 Jaya Ruth Asirvatham, M.B.B.S., Julie M. Jorns, M.D.. Breast - Fibrocystic changes - Sclerosing adenosis. Pathology Outlines. Topic Completed: 1 January 2015. Minor changes: 31 December 2020