Smooth muscle tumor

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Author: Mikael Häggström [notes 1]

Smooth muscle tumor (in this case leiomyoma).

Gross processing

Gross examination

Examine and describe:[1]

  • Location
  • Number of tumors, if multiple
  • Size
  • Demarcation


In case of hysterectomy, submit pieces from all smooth muscle tumors >5 cm in diameter.[1]

Submit any macroscopically abnormal parts of the tumors (hemorrhagic, necrotic, brittle or softening areas, and areas with blurry delimitation).[1]

Microscopic examination

Distinguish leiomyoma (benign) from leiomyosarcoma (malignant).

Further information: Evaluation of tumors

Microscopic report


  • Microscopic findings, including any visible linings
  • Diagnosis or most probable one
  • Any linings or borders.

Example, for a cervical polyp:

Polyp lined by a single layer of columnar epithelium consistent with endometrium. The interior consists of smooth muscles in a whorled pattern. No atypia. The finding is consistent with a pedunculated submucosal leiomyoma.

See also: General notes on reporting


  1. For a full list of contributors, see article history. Creators of images are attributed at the image description pages, seen by clicking on the images. See Patholines:Authorship for details.

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  1. 1.0 1.1 1.2 Monica Dahlgren, Janne Malina, Anna Måsbäck, Otto Ljungberg. Stora utskärningen. KVAST (Swedish Society of Pathology). Retrieved on 2019-09-26.
  2. Mohamed Mokhtar Desouki. Uterus - Stromal tumors - Leiomyoma. pathology Outlines. Topic Completed: 1 August 2011. Revised: 15 December 2019
  3. Vijay Shankar, M.D.. Soft tissue - Smooth muscle - Leiomyosarcoma - general. Pathology Outlines. Topic Completed: 1 November 2012. Revised: 11 September 2019