Template:Usual ductal hyperplasia versus atypical ductal hyperplasia
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In contrast to usual ductal hyperplasia (UDH), atypical ductal hyperplasia (ADH) displays:[1]
- Increased amounts of pale eosinophilic to amphophilic cytoplasm with conspicuous cell borders
- Atypical architectural patterns, including cribriform spaces, Roman arches, trabecular bars and micropapillae
If uncertain, immunohistochemistry can be performed:[1]
| Usual ductal hyperplasia (UDH) | Atypical ductal hyperplasia (ADH) | |
| High molecular weight keratins | Mosaic to occasionally diffuse | Negative |
| Estrogen receptor | Heterogenous staining | Diffusely positive |
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References
- ↑ 1.0 1.1 Sofia Lérias, M.D., Melinda Lerwill, M.D.. Usual ductal hyperplasia. Pathology Outlines. Last author update: 11 February 2021. Last staff update: 25 April 2022
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